Skip to main content

Physical Science:

Subsection 8.3.3 Free Radicals

Free radicals are atoms or molecules that have an unpaired electron in their outermost shell. They form when covalent bond is broken. In this case each of these molecules or atoms hold the same number of protons and electrons in them but because of unpaired electron/s in the orbit they become very reactive. They are highly reactive and unstable because they seek to pair their unpaired electron with another electron, either from another molecule or from another part of the same molecule. This process can cause damage to cells and tissues, and has been implicated in several diseases, including cancer, heart disease, and aging. Free radicals can be generated through normal metabolic processes in the body, as well as through exposure to radiation, pollution, cigarette smoke, and certain chemicals. Some of the most common free radicals in the body include superoxide, hydroxyl, and nitric oxide radicals. To neutralize free radicals, the body relies on antioxidants, which are molecules that can donate an electron to the free radical without becoming unstable themselves. Antioxidants can be obtained from a variety of sources, including fruits, vegetables, nuts, and seeds. Vitamins C and E, beta-carotene, and selenium are all examples of antioxidants that can help neutralize free radicals in the body.
Free radicals are formed when a covalent bond in a molecule is broken with each fragment taking one of the shared electrons of the bond. For example when water molecules is broken
\begin{equation*} HOH \rightarrow H\cdot + \cdot OH \end{equation*}
The dots are unpaired electrons. Here \(\cdot OH\) is called a hydroxyle radical.